Crazy Coumadin

Widely used blood thinner warfarin will come with new instructions explaining that people with certain genes may need a lower dose to take the drug safely, U.S. health officials said on Thursday.

The change is part of a move toward personalized medicine in which doctors tailor treatment based on genetic makeup, the Food and Drug Administration said.

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I'm not sure of the cost effectiveness of a genetic test to figure out a dose of coumadin. When the medication is started in the hospital, with daily PT/INR monitoring, and reasonable dosing, patients really shouldn't become hypertherapeutic.

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